| Assignment | Topic/Topic Question |
| Pico 1 | In adults presenting to the Emergency Department with minor head trauma and mild scalp hematoma, does routine head CT imaging compared to clinical decision rule guided management without CT safely identify clinically significant intracranial injury while reducing unnecessary imaging? |
| Pico 2 | In adults with severe metabolic acidosis due to starvation and underlying chronic kidney disease, does intravenous sodium bicarbonate compared to supportive care alone improve acidosis resolution, hemodynamic stability, and clinical outcomes? |
| Pico 3 | In adults with traumatic lacerations, how does closure with tissue adhesive compare to sutures in regards to cosmetic outcome, wound healing, and lower complication rates? |
| Pico 4 | In adults with recurrent common bile duct stones, does a single-stage surgical approach, laparoscopic cholecystectomy with intraoperative stone clearance, compared to a two-stage approach, preoperative ERCP followed by cholecystectomy, result in shorter total hospital stays, higher stone clearance rates, and a lower risk of post-procedural complications? |
| Pico 5 | In post-mastectomy patients with radiation-induced skin damage, does autologous fat grafting compared to standard care (no grafting) significantly improve skin elasticity, texture, and tissue compliance? |
| Pico 6 | In adults with symptomatic BPH, does water vapor thermal therapy (Rezum) compared to traditional transurethral resection of the prostate (TURP) result in a comparable improvement in International Prostate Symptom Score (IPSS)? |
| MiniCat 1 Draft | Does the transaxillary incision, compared with the inframammary incision, result in a significantly different rate of Baker Grade III/IV capsular contracture or Surgical Site Infection (SSI) in women undergoing primary submuscular breast augmentation at 2-year follow-up? |
| MiniCat 1 Final | Does the transaxillary incision, compared with the inframammary incision, result in a significantly different rate of Baker Grade III/IV capsular contracture or Surgical Site Infection (SSI) in women undergoing primary submuscular breast augmentation at 2-year follow-up? |
| PICO 7 | In older adults with chronic or refractory constipation, is oral Polyethylene Glycol (PEG) more effective than oral Lactulose at increasing weekly bowel movement frequency and improving stool consistency? |
| PICO 8 | In adults with poorly controlled Type 2 diabetes managed on basal insulin, does the use of a continuous glucose monitor (CGM) compared to traditional finger-stick self-monitoring of blood glucose (SMBG) result in a greater reduction in HbA1c and improved time-in-range (TIR) over a 6-month period? |
| PICO 9 | In adults hospitalized with acute decompensated heart failure, does the administration of continuous infusion loop diuretics compared to intermittent intravenous bolus dosing result in greater net fluid loss and a shorter length of hospital stay? |
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